Cafgrain Tablet

Last Updated: March 26th, 2026

Cafgrain Tablet is a product of Agrosaf Pharmaceuticals

Composition: Caffeine (100mg) + Ergotamine (1mg) + Paracetamol (250mg) + Prochlorperazine (2.5mg)

₹ 124.69

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

Banned For Sale

All Details About Cafgrain Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Cafgrain Tablet

Description:

Cafgrain Tablet is a medicine used to prevent and treat migraine. It blocks the release of certain chemical messengers that cause pain and inflammation. It also blocks the signals in the brain that cause nausea and vomiting associated with migraine.

Cafgrain Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are using it for and how well it helps your symptoms. Employ it regularly and do not discontinue using it until the doctor tells you it is alright to stop.

It may cause side effects like sedation, orthostatic hypotension (sudden lowering of blood pressure on standing), drowsiness, urinary retention, and dryness in mouth in some patients. If you experience any of such side effects that do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. In general, you should try to use the smallest amount necessary to control your symptoms.

Earlier using the medicine, you should tell your doctor if you have any other illnesses or disorders. It may also affect, or be affected by, some other medicines you are using so let your doctor know all the other medicines you are taking. It should be used with caution in patients who are alcoholic or have liver or kidney disease. Pregnant and breastfeeding women should consult their doctors first before using the medicine.

Uses:

Migraine

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cafgrain Tablet should be taken with or after food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Cafgrain

Orthostatic hypotension (sudden lowering of blood pressure on standing)
Drowsiness
Increased heart rate
Urinary retention
Muscle pain
Dryness in mouth
Constipation
Sedation

Warning & Precautions:

Alcohol

UNSAFE

It is unsafe to consume alcohol with Cafgrain Tablet

Pregnancy

UNSAFE

Cafgrain Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Cafgrain Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Occasional short-term use of Cafgrain Tablet for the treatment of nausea and vomiting poses little risk to the breastfed infant.

Driving

UNSAFE

Cafgrain Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Cafgrain Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Cafgrain Tablet is unsafe to use in patients with liver disease and should be avoided.

FAQs:

What is Cafgrain Tablet?

Cafgrain Tablet is a combination of four medicines: Paracetamol, Ergotamine, Caffeine and Prochlorperazine. This medicine is used in the treatment of migraine symptoms like a headache, nausea and vomiting. Ergotamine prevents blood vessels in the head from expanding. Caffeine increases the absorption of ergotamine and also narrows the widened blood vessels. Paracetamol blocks the release of certain chemical messengers in the brain that causes pain. Prochlorperazine is an antiemetic which prevents vomiting by blocking signals to the part of your brain that cause nausea/vomiting.

What can cause or trigger a migraine attack?

Self-assured physical or environmental factors, such as foods, hormonal changes, weather and stress can lead to or “trigger” a migraine. However, it is important to remember that triggers can be different for everyone. That is why, to help prevent migraine attacks, you need to figure out which triggers affect you and which ones do not. Retaining a headache diary is an effective way to track triggers, and it will help you talk to your healthcare professional about your condition.

Can I stop taking Cafgrain Tablet when my migraine symptoms are relieved?

Cafgrain Tablet is usually used for prevention and treatment of migraine attack. Cafgrain Tablet should be continued as advised by the doctor.

Can the use of Cafgrain Tablet cause constipation?

Affirmative, the use of Cafgrain Tablet can cause constipation. Lifestyle changes like eating a good amount of high-fiber foods such as fresh fruits, vegetables and cereals, drinking plenty of water or other fluids and regular exercise can help relieve constipation.

Can the use of Cafgrain Tablet cause dry mouth?

Affirmative, the use of Cafgrain Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy and salty.

Can I take a higher than the recommended dose of this medicine?

No, taking a higher than the recommended dose of Cafgrain Tablet can increase the risk of side effects. If you are experiencing increased severity of migraine attacks which are not relieved by the recommended dose of this medicine, please consult your doctor for re-evaluation.

Does Cafgrain Tablet expire?

Affirmative, Cafgrain Tablet does expire. Please check the expiry date written on the pack of this medicine. Do not use Cafgrain Tablet after the expiry date.

What is Cafgrain Tablet?

What is a migraine?

A migraine is characterized by severe throbbing pain on one side of the head. The pain is usually pulsating in nature and is accompanied by nausea, vomiting, and sensitivity to light, sound and smell. The symptoms and severity vary from person to person.

What can cause or trigger a migraine attack?

Can I stop taking Cafgrain Tablet when my migraine symptoms are relieved?

Cafgrain Tablet is usually used for prevention and treatment of migraine attack. Cafgrain Tablet should be continued as advised by the doctor.

Can the use of Cafgrain Tablet cause constipation?

Can the use of Cafgrain Tablet cause dry mouth?

Can I take a higher than the recommended dose of this medicine?

Does Cafgrain Tablet expire?

Affirmative, Cafgrain Tablet does expire. Please check the expiry date written on the pack of this medicine. Do not use Cafgrain Tablet after the expiry date.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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