Bosenat 125 Tablet 10.0 tablets in 1 strip

Last Updated: March 24th, 2026

Bosenat 125 Tablet is a product of Natco Pharma Ltd

Composition: Bosentan (125mg)

Pack of 10 tablet

₹ 1274.33

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

All Details About Bosenat 125 Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Bosenat 125 Tablet

Description:

Bosenat 125 Tablet is a prescription medicine used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart to the lungs). It even helps to improve your quality of life, exercising ability and delay in disease progression.

Bosenat 125 Tablet should be taken with or without food. This medicine should be used regularly to get the most benefit from it. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.

The most common side effects of this medicine include headache, swelling of the legs and ankles, and diarrhea. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Some serious side effects which mean your doctor should know immediately include Anemia (low number of red blood cells) and abnormal liver function such as nausea, vomiting, dark urine, fever, and dark urine. Your doctor might check you for blood tests to check for anemia and liver function.

Earlier taking this medicine, let your doctor know if you have liver dysfunctioning. Inform your doctor if you are pregnant or breastfeeding. Women are suggested to use reliable contraceptive pills to avoid pregnancy and should continue even after one month of stopping the treatment. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.

Uses:

Pulmonary arterial hypertension (PAH)

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bosenat 125 Tablet may be taken with or without food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Bosenat

Headache
Ankle swelling
Edema (swelling)
Diarrhea
Anemia (low number of red blood cells)
Respiratory tract infection

Warning & Precautions:

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Bosenat 125 Tablet may cause excessive drowsiness when taken with alcohol.

Pregnancy

UNSAFE

Bosenat 125 Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

CONSULT YOUR DOCTOR

Bosenat 125 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Bosenat 125 Tablet may cause side effects that could affect your ability to drive.
As Bosenat 125 Tablet can induce hypotension (decrease of your blood pressure) which can make you feel dizzy and this can affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Bosenat 125 Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.

Liver

CAUTION

Bosenat 125 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Employ of Bosenat 125 Tablet is not recommended in patients with moderate and severe liver disease.

FAQs:

How is Bosenat 125 Tablet administered?

Bosenat 125 Tablet is given as a tablet form and can be taken with or without food. The tablets are to be taken twice daily in the morning and evening. The exact dosage and frequency of dose will be decided by the doctor on the basis of age and weight of the patient.

Are there chances of anemia with Bosenat 125 Tablet?

Affirmative, there are chances that Bosenat 125 Tablet may cause anemia. It can cause a dose-related decrease in hemoglobin in the blood which could lead to anemia. Regular hemoglobin check is advised while taking this medicine and consult your prescribing doctor for his advice. In some cases, blood transfusion is done to treat anemia.

Can I take Bosenat 125 Tablet if I have liver problems?

It has been found that in some cases Bosenat 125 Tablet can cause liver damage in patients who are prone to have liver disease. This medicine can also lead to increased liver enzymes. Hence, it should be used with caution in prone patients or in patients with history of liver disease. Earlier starting the medication inform your doctor if you have had a history of liver disease.

Is Bosenat 125 Tablet safe in pregnancy?

No, Bosenat 125 Tablet is not safe during pregnancy. There is evidence to show that it can cause major birth defects in the newborn baby and can harm the baby in womb. It is not advised to take Bosenat 125 Tablet if you are planning to become pregnant. You should use reliable contraception methods while you take Bosenat 125 Tablet. Consult your doctor before starting this medication or planning pregnancy.

Written by:
Dr. Lokanish
M.B.B.S.

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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