Amfosted 500 Injection 1 Injection in 1 vial

All Details About Amfosted 500 Injection

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Amfosted 500 Injection

Description:

Amfosted 500 Injection is used to prevent dryness in the mouth after radiotherapy of head and neck cancer. It reduces the harmful effect of chemotherapy on the kidneys during treatment with cisplatin (medicines used to treat cancer).

Amfosted 500 Injection is given as an injection into vein (IV infusion) under the supervision of doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Nausea, vomiting, decreased blood pressure, sleepiness, dizziness, and flushing are some common side effects of this medicine. Consult with your doctor if it does not go away or bothers you. It is advised to stay hydrated before taking this medicine. You will be check for blood pressure before infusion and every 5 minutes during infusion.

Earlier taking it, tell your doctor if you have heart diseases such as irregular heartbeat and heart failure, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using.

Uses:

Treatment of Dryness in the mouth after radiotherapy of head and neck cancer

Directions For Use:

Ordinary side effects of Amfosted

Nausea
Vomiting
Decreased blood pressure
Hiccup
Sleepiness
Dizziness
Flushing (sense of warmth in the face, ears, neck and trunk)
Fever
Chills

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Warning & Precautions:

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Amfosted 500 Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Amfosted 500 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Amfosted 500 Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Amfosted 500 Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

SAFE IF PRESCRIBED

Amfosted 500 Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Amfosted 500 Injection may not be needed in these patients. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Amfosted 500 Injection in patients with liver disease. Please consult your doctor.

FAQs:

Q. Is Amfosted 500 Injection FDA approved?

Affirmative, it is FDA an approved drug

Q. What is Amfosted 500 Injection used for?

Amfosted 500 Injection is used to reduce toxicity to kidneys associated with cisplatin therapy in patients with advanced ovarian cancer, and in prevention of dry mouth (xerostomia) during radiotherapy for head and neck cancer

Q. How does Amfosted 500 Injection work?

It protects the normal cells against the harmful effects of chemotherapy medications and radiation treatment by producing a chemical ‘thiol' that binds to and detoxifies the harmful compounds produced by cisplatin. Amfosted 500 Injection does not interfere with the action of cisplatin.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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