Adesum 400mg Tablet 10.0 tablets in 1 strip

Last Updated: March 26th, 2026

Adesum 400mg Tablet is a product of Sun Pharmaceutical Industries Ltd

Composition: S-Adenosyl L-Methoinine Disulfate Tosylate (400mg)

Pack of 10 tablet

₹ 29.30

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All Details About Adesum 400mg Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Adesum 400mg Tablet

Description:

Adesum 400mg Tablet is a medicine used for the treatment of liver disease associated with reduced bile formation (intrahepatic cholestasis). It protects the liver cells from toxins and helps the liver to perform its normal functions.

Adesum 400mg Tablet may be taken with or without food. The dose will depend on the severity of your condition and your body weight. It is best swallowed whole, but you may need to break them to get the correct dose. This medicine needs to be taken regularly to get the most benefit and you may have to take it for several months or longer, so try to get into a routine. Retain using it as prescribed even if your symptoms disappear.

Employ of this medicine may cause some common side effects such as headache, dizziness, vomiting, upset stomach, diarrhea, constipation, and insomnia. Not everyone gets side effects. If you are worried about them, or they do not go away, let your doctor know. If you have problems with diarrhea your doctor may reduce the dose or stop the treatment. Drink enough water or fluids to stay hydrated in case of severe diarrhea and constipation.

Earlier taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy, or breastfeeding. Using this medicine can reduce or increase the effect of some other medicines so tell your doctor, all other medicines you are taking. Avoid drinking alcohol as it might increase side effects.

Uses:

Treatment of Liver disease

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Adesum 400mg Tablet may be taken with or without food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Adesum

Headache
Dizziness
Vomiting
Agitated stomach
Diarrhea
Constipation
Insomnia (difficulty in sleeping)

Warning & Precautions:

Alcohol

UNSAFE

It is unsafe to consume alcohol with Adesum 400mg Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Adesum 400mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Adesum 400mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Adesum 400mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Adesum 400mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Adesum 400mg Tablet is safe to use in patients with liver disease. No dose adjustment is recommended.

FAQs:

What is Adesum 400mg Tablet used for?

Adesum 400mg Tablet is used to treat liver diseases where bile flow is reduced (intrahepatic cholestasis). It protects liver cells from harmful substances and helps the liver function normally.

How does taking Adesum 400mg Tablet help with joint pain?

Adesum 400mg Tablet is usually used to support liver health, but due to its anti‑inflammatory properties, it can also help reduce pain and improve joint function, similar to common arthritis medicines but with fewer side effects. Your doctor will evaluate the need for this medicine and advise on the dose and duration for the best results.

Can Adesum 400mg Tablet improve symptoms of depression?

Adesum 400mg Tablet is usually used to support liver health. However, some people find that it helps improve mood and reduce depression symptoms. Forever use this medicine only as prescribed by your doctor.

Is Adesum 400mg Tablet natural or synthetic?

Adesum 400mg Tablet contains SAMe, which is a natural compound made by the body but can also be taken as a synthetic supplement to increase low levels.

Can Adesum 400mg Tablet help liver problems?

Adesum 400mg Tablet can support liver function and help protect liver cells. Your doctor will prescribe the dose and duration of this medicine for the best results.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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